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Protein C deficiency
Protein C is a natural anticoagulant chemical in the blood. The deficiency can be genetic, or due to other conditions such as kidney disease. With inherited protein C deficiency, the risk of a blood clot forming varies between families. This is because each family has a different alteration in the protein C gene. The best guide to your level of risk is whether you or your relatives have had a blood clot. If a child inherits two genes with protein C deficiency (one from each parent - this is very rare), they will have a more severe problem. They will get blood clots in the skin soon after birth (a condition called purpura fulminans). This is treated with protein C concentrates and blood-thinning (anticoagulant) medication