REDDY MEDICAL COMMUNICATIONS
Thrombophilia is a condition where the blood has an increased tendency to form clots. Blood clots can cause problems such as deep vein thrombosis (DVT) or pulmonary embolism. There are different types of thrombophilia - some are inherited and some are acquired, meaning they usually develop in adult life. Often thrombophilia is mild. Many people with thrombophilia do not have problems from their condition. Blood tests can diagnose the problem. Thrombophilia does not always require treatment but some people need to take aspirin or warfarin. If you have thrombophilia, be aware of the symptoms of a blood clot and get treatment immediately if you have symptoms.
Protein C deficiency
Protein S deficiency
Heparin CofactorII deficiency
Abnormalities of Fibrinolysis
Plasminogen deficiency Type I
Plasminogen deficiency Type II
Decreased levels of tPA
Decreased levels of PAI-1
Elevated levels of TAFI
Acquired thrombophilias are not inherited, and usually start in adulthood.
Antiphospholipid syndrome (APS).
Other acquired conditions
Other conditions can increase the risk of a blood clot. Some doctors classify these as thrombophilias. Examples are certain disorders affecting platelets, some bone marrow disorders, some kidney problems, inflammatory bowel disease and advanced cancer.
Mixed inherited/acquired thrombophilias
Paroxysmal nocturnal haemoglobinuria
Elevated factor VIII